Now showing items 31-40 of 941
Robust microbial fabrication of plant pharmaceuticals: Complexities and solutions
Abstract not available.
Role of the varicella zoster virus ORF9 protein in viral replication
The varicella zoster virus (VZV) ORF9 protein is a member of the herpesvirus UL49 gene family but shares limited identity and similarity with the UL49 prototype, HSV-1 VP22. ORF9 mRNA is the most abundantly expressed message ...
The role of DNA replication in mismatch repair
DNA Mismatch Repair (MMR) plays an important role in maintaining genomic fidelity and stability in all living organisms, ranging from bacteria to humans, and is known to be closely associated with DNA replication and present ...
An emulsion of dodecafluoropentane (DDFPe) sustained oxygen delivery in spontaneously breathing swine after hemorrhagic shock
Twelve spontaneously air breathing anesthetized male swine had a 48.7 ± 0.55 (s.e.) % reduction of their circulating blood volume through a controlled hemorrhage. The large decrease in the swines' circulating blood volume ...
Dissection of the SSeCKS metastasis suppressor gene promoters: Identification of v-Src responsive elements
SSeCKS ( S rc- S uppressed C k inase S ubstrate), also called gravin/AKAP12, is a large scaffolding protein with metastasis suppressor activity. Two major isoforms of SSeCKS are expressed in most cell and tissue types under ...
Characterization of pentatricopeptide repeat (PPR) proteins in Trypanosoma brucei
Pentatricopeptide repeat proteins (PPRs) are one of the largest newly identified protein families. PPR is characterized by the presence of a tandemly repeated 35 amino acids motif. It is extremely abundant in plants, and ...
Defining mechanisms by which fever-range thermal stress regulates natural killer cell mediated recognition and killing of tumor cells
All circulating cells, including Natural Killer (NK) cells, normally experience temperature gradients as they move through compartments in the body; however inflammation-driven febrile conditions can expose them to elevated ...
Defining functional motifs within interleukin-17 receptor cytoplasmic tail
Interleukin-17 and its receptors are members of a proinflammatory cytokine family. The IL-17 receptor complex (composed of two subunits, IL-17RA and IL-17RC) is ubiquitously expressed, and cytoplasmic tails of the subunits ...
THz dielectric response of lysozyme and Photoactive Yellow Protein
The primary goal of this dissertation was to elucidate and quantify the physical basis of protein flexibility at terahertz (THz) frequencies in two distinct systems: lysozyme and Photoactive Yellow Protein (PYP). To this ...
Mechanisms of DNA repair and damage tolerance in Pseudomonas aeruginosa: Implications for cystic fibrosis patients
P. aeruginosa is a human opportunistic pathogen that chronically infects the lungs of cystic fibrosis patients and is the leading cause of morbidity and mortality of people afflicted with this disease. A striking correlation ...