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FACT is an accelerator of tumorigenesis, a marker of aggressive, undifferentiated cancers, and a potential therapeutic target

Garcia, Henry Alexander (2014)

Facilitates Chromatin Transcription (FACT) is a heterodimeric complex of subunits SSRP1 and Spt16 that is involved in chromatin remodeling during transcription, replication, and DNA repair. FACT was thought to be ubiquitously ...