Now showing items 1-8 of 8
System-level modeling and analysis of biological reaction networks in signal transduction and glycosylation
Novel high-throughput genomic and proteomic tools are allowing the integration of information from a range of biological assays into a single conceptual framework. This framework is often described as a network of biochemical ...
A web-based modeling approach for tracking algal blooms in lower Great Lakes
The occurrence of algal blooms in the Great Lakes has been a growing concern over the past few decades, especially for toxic or harmful algal blooms (HABs). For the present work a general circulation model is used to help ...
Structure-property relationships in associating polymer solutions
Abstract not available.
High yield anthocyanin biosynthesis in metabolic engineering Escherichia coli
Anthcoyanins, the largest sub-group of flavonoids and a major group of plant pigments, impart the eye-catching hues to most flowers and fruits ranging from pink through red and purple to dark blue. They are widely distributed ...
Resource shed delineation in Lake Erie
Many of the major ecological issues concerning Lake Erie, which include harmful algal blooms, spread of invasive species and toxin distribution, involve spatially explicit phenomena. In order to control these phenomena, a ...
Using molecular simulation to explore protein and colloidal phase behavior in bulk, confinement, and mixtures
Because of the ubiquity of colloidal solutions in everyday industrial applications such as papermaking and coatings there is a need to be able to efficiently design and manufacture these substances. A related issue concerns ...
Correlating in-vivo hemodynamics with vascular responses
The roles of hemodynamics in the natural history of vascular diseases remain unclear due to a lack of understanding of the cellular and molecular responses under various hemodynamic stimuli. In vivo quantitative hemodynamics, ...
Constructing microbial production platform for the biosynthesis of natural drug candidates-flavonoids
The current dissertation investigated the construction of production platforms for the synthesis of flavonoids in both prokaryotic host E. coli and eukaryotic host yeast S. cerevisiae. The total flavonoid biosynthetic ...