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Development of Nano-Liposomal Formulations of Epidermal Growth Factor Receptor Inhibitors and their Pharmacological Interactions on Drug-Sensitive and Drug-Resistant Cancer Cell Lines
(2010)
A rapidly expanding understanding of molecular derangements in cancer cell function has led to the development of selective, targeted chemotherapeutic agents. Growth factor signal transduction networks are frequently ...
Glycan Signature Changes in Stem Cell Differentiation and Cancer
(2012)
Glycosyltransferase (glycoT) enzymes mediate the transfer of monosaccharide from nucleotide-sugars to carbohydrate, lipid and protein based acceptors leading to formation of glycans. The regulation of the glycan structures ...
Redirecting cancer kinase signaling: A novel rewiring of Bcr/Abl and PKC Beta II
(2016)
Mutations in cancer very frequently cause aberrant signal transduction. This dysfunctional signaling blocks apoptotic and differentiation pathways, activates proliferative and survival pathways, and plays a central role ...
Redirecting cancer kinase signaling: A novel rewiring of Bcr/Abl and PKC Beta II
(2016)
Mutations in cancer very frequently cause aberrant signal transduction. This dysfunctional signaling blocks apoptotic and differentiation pathways, activates proliferative and survival pathways, and plays a central role ...
Redirecting cancer kinase signaling: A novel rewiring of Bcr/Abl and PKC Beta II
(2016)
Mutations in cancer very frequently cause aberrant signal transduction. This dysfunctional signaling blocks apoptotic and differentiation pathways, activates proliferative and survival pathways, and plays a central role ...