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Developing computational and molecular tools to engineer the microbial biosynthesis of natural products
This dissertation represents an effort in the expanding field of metabolic engineering. Designing cellular phenotypes using metabolic engineering principles for the production of natural products is becoming an increasingly ...
Constructing microbial production platform for the biosynthesis of natural drug candidates-flavonoids
The current dissertation investigated the construction of production platforms for the synthesis of flavonoids in both prokaryotic host E. coli and eukaryotic host yeast S. cerevisiae. The total flavonoid biosynthetic ...