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Metabolic engineering of Escherichia coli and Saccharomyces cerevisiae to mutasynthesize natural phenylpropanoids and novel analogs
The current dissertation investigated the biosynthesis of natural and unnatural flavonoids using Escherichia coli and Saccharomyces cerevisiae. Flavonoids are a diverse group of secondary metabolites found ubiquitously in ...
Metabolic engineering for high-level flavonoids and stilbenes production in microorganisms
This dissertation represented an effort in efficient biosynthesis of both natural and unnatural stilbenes and flavonoids in microbial platform utilizing state of the art metabolic engineering strategies. Flavonoids are ...
Biosynthesis of anthocyanin in metabolically engineered Escherichia coli
Anthocyanins are water-soluble colored pigments found in terrestrial plants. They are responsible for the red, blue and purple coloration of many flowers, fruits and other plant parts. Anthocyanins have been known to possess ...
Constructing microbial production platform for the biosynthesis of natural drug candidates-flavonoids
The current dissertation investigated the construction of production platforms for the synthesis of flavonoids in both prokaryotic host E. coli and eukaryotic host yeast S. cerevisiae. The total flavonoid biosynthetic ...