Now showing items 81-86 of 86
Localization and semi-quantitation of NMDA2A and NMDA2B receptor mRNAs in auditory cortex
NMDA (N-methyl-d-aspartate) receptors are essential for learning and formation of memory. Recent research reported that expression of NMDA2A and NMDA2B receptor mRNAs in the cortices of adult rats decreased after intensive ...
Study of the effect of tungsten shields on the radiation dose delivery in a gynecological applicator using Gafchromic film dosimetry
Fletcher Suit Delclos applicator is employed for high dose rate intracavitary brachytherapy treatment of cervical cancer. It includes tungsten shields in the direction of bladder and rectum to limit their radiation exposure. ...
Studies of structure, hydration and dynamics of biological macromolecules by use of NMR spectroscopy
Nuclear magnetic resonance (NMR) has emerged as a powerful tool for studying biological macromolecules in aqueous solution. This dissertation describes the efforts to study the structure, hydration and dynamics of biological ...
The role of RIP ubiquitination in the TNFalpha signaling pathway
Stimulation of cells by TNFα triggers recruitment of various signaling molecules, including RIP, to the TNFα receptor 1 complex, which leads to activation of NF-κB. Previous studies indicate that RIP plays an essential ...
Effects of conjugated linoleic acid on stromal cells in the mammary gland
Stromal cells represent a novel target for chemopreventively modifying the breast microenvironment. The purpose of these studies was to test the hypothesis that conjugated linoleic acid (CLA) acts chemoprotectively against ...
Acquired rituximab resistance is associated with cross-resistance to chemotherapy that is overcome by treatment with bortezomib
Despite recent advances in therapy, acquired resistance is common among patients with B-cell non-Hodgkin's lymphoma (B-NHL). Targeting malignant B-cells using the anti-CD20 monoclonal antibody rituximab has improved the ...