Cyclodextrin effects on surfactant self-assembly
Grandin, Heidi Lin
MetadataShow full item record
The spontaneous organization in aqueous solution of amphiphilic molecules such as surfactants, lipids, or copolymers is of great fundamental (e.g., cell membranes) and technological (e.g., pharmaceutical, personal care, and coating formulations) interest. The self-assembly of amphiphiles is dictated by their inherent properties (e.g., chemical composition and molecular architecture) but also by their surroundings (e.g., solvent, temperature). It is often desirable or advantageous to modulate self-assembly in water by adding organic solvents and/or solutes. The work presented in this thesis contributes to our knowledge of how the self-assembly of typical surfactants into micelles is affected by the presence of cyclodextrins (CDs), cyclic oligosaccharides which can complex with the hydrophobic domains of the surfactant through a molecular recognition mechanism.