Design, performance analysis, and optimization of a new X-ray detector for region of interest angiography and fluoroscopy for implementation in neurovascular interventional procedures
Josan, Gaurav C
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Image guided neuro-interventions require high spatial resolution, about 4 to 10 lp/mm, for visualization of small vessels called perforators which maybe 50-300 μ m in diameter, and for precise localization of interventional devices like stents and especially new asymmetric stents. This high resolution is of the same order as that required in mammography but in these procedures it is required at higher energies and higher frame rates. An optimal detector for application in these procedures with high energy, high resolution and dynamic capabilities is not available currently and this work is an effort in this direction. A new region of interest micro-angiographic fluoroscopic detector is being developed by our group. Design, optimization and complete performance analysis of this detector was accomplished as a part of this thesis work. This detector is capable of acquiring 30 fps at both fluoroscopic exposures in the fractional μ R and higher range as well as at angiographic exposures in the mR range. The detector with a field of view of 60 mm and limiting spatial resolution greater than 9.4 lp / mm , is capable of variable pixel sizes ranging between 38 μ m and 53 μ m . Complete linear systems analysis of this detector resulted in a value of MTF greater than 1% at Nyquist frequency and the value of DQE(0) of around 59.5%. It has been demonstrated that this new detector technology would allow improved treatments and development of smaller interventional devices and catheter based systems.