Effects of deep brain stimulation of the subthalamic nucleus on activities of daily living skills in people with Parkinson's disease
Krupinski, Dani Lyn M
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This study objectively examined the effects of subthalamic nucleus deep brain stimulation on performance of activities of daily living (ADLs) in people with Parkinson's disease using the Functional Independence Measure (FIM(TM)) and the Physical Performance Test (PPT). Seven participants with Parkinson's disease who had deep brain stimulation electrodes implanted completed this study. They were evaluated with both measures while on medication in two conditions of stimulation, "on" and "off." The hypotheses were (a) when deep brain stimulation was "on," participants would demonstrate higher ADLs scores than when stimulation was "off," (b) the FIM(TM) and the PPT would be reliable measurements for assessing ADLs in Parkinson's disease. ADLs scores were significantly improved in the stimulation "on" condition compared to the stimulation "of" condition for the FIM(TM) (T=-2.37, p≤.01) and the PPT (T=-2.21, p≤.01). A positive correlation was found between session 1 and session 2 for both measures demonstrating reliability.