A Simple and Portable Micromixing Device Based on Capillary and Vacuum Driven Microfluidic Systems
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Micromixing is an important part in microfluidics for both multicomponent analytical systems and microreaction technology. The objective of this thesis is to develop a simple and portable micromixing device based on capillary and vacuum driven micrifluidic systems, without using complicated controllable pumping methods. This microfluidic device that has been designed, fabricated and characterized here can be used for effective mixing of two different liquids simply by using a syringe. In this device, a pressure balancer is also integrated to balance the pressure difference between two liquids caused by bare handed operation in actual experiments. For the purpose of testing the performance of this proposed device, I firstly utilized it to mix two dye water liquids in different colors and detected the mixture through color change. The mixing performance of liquids with different initial loading volume difference has also been tested in the following experiments. Then, as an application of the device, human blood groups of A, B and O have been successfully determined by viscosity change due to the agglutination reaction.