lntegrated Pulmonary lndex Compared to Pulse Oximetry in ldentifying Opioid-lnduced Respiratory Depression
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Problem under investigation: Despite the frequency of opioid use throughout the perioperative period, there are no universally accepted guidelines to directly monitor respiratory depression Objective: Compare the effectiveness of the Integrated Pulmonary Index (IPI) to pulse oximetry (SpO2) in detecting Opioid-Induced Respiratory Depression (OIRD) Background Literature/Theoretical Framework: There is vast research supporting the use of IPI for respiratory monitoring. Roy’s adaptation model provides the theoretical basis needed to utilize IPI and guide postoperative analgesic regimens. Project Methods: Obtain preoperative IPI and SpO2 baselines from the subjects and monitor the number of OIRD instances postoperatively. Data Analysis: A Spearman’s correlation was run to determine the relationship between the IPI and SpO2 values. The Friedman’s test was utilized to determine the difference in specificity of the monitoring tools. The Wilcoxon signed-rank test was used to compare monitoring precision between grouped variables. Results: There is a positive correlation between IPI and SpO2, which is significant (r=0.519, p=0.003). The Wilcoxon Sign-Rank test did not find a difference in the precision between SpO2 and IPI. Conclusion: IPI and SpO2 demonstrate a positive correlation for detecting OIRD postoperatively in orthopedic patients undergoing total knee or hip replacement.