Browsing Theses and Dissertations (ETDs) by Issue Date
Now showing items 1-20 of 1041
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Determinants of Pharmacodynamic Heterogeneity in Multiple Myeloma Cells
(State University of New York at Buffalo, 2017)Multiple myeloma is a complex heterogeneous hematological malignancy comprising of rapidly proliferating genetically diverse clonal plasma cells. Tumor initiation, development, and progression occur through a series of ... -
Bioorthogonal Chemistry for Protein Labeling in Live Cells
(State University of New York at Buffalo, 2018)Chapter one provides an overview of bioorthogonal reactions commonly used in the chemical biology field. Chapter two describes the synthesis of a BODIPY-tetrazole and its use as an “off-on” reporter of hydrogen peroxide ... -
Innovations in Test Phantom Metrology for Ultrasonic Imaging in relation to Medical Imaging, Biometric Characterization, and 3-Dimensional Microfluidic Applications
(State University of New York at Buffalo, 2018)This dissertation discusses the design, fabrication, and testing of a series of test phantoms for the testing and validation of a series of applications. These test phantoms focused on the replications of key physiological ... -
Contrasting Hydroclimate Response of Coastal Norway and Arctic Russia During Late-Glacial and Holocene Climate Change
(State University of New York at Buffalo, 2018)Reconstructing changes to the δ2H of precipitation through time as recorded in leaf wax hydrogen isotopes (δ2Hwax) can provide substantive information about changes to local hydroclimate, incorporating influences from the ... -
Investigation of Inter-Individual Variability in Monoclonal Antibody Disposition
(State University of New York at Buffalo, 2018)Substantial inter-individual variability (IIV) in monoclonal antibody (mAb) pharmacokinetics has been reported in the clinic. The sources of variability are not well understood and often not explored. Very few preclinical ... -
Representing 9/11: Intermediality, Plurality and Temporality
(State University of New York at Buffalo, 2018)The September 11 attacks have been often referred to as an unprecedented historical event defining the twenty-first century. Live broadcasts of the event in real time have rendered 9/11 an unprecedented visual disaster ... -
Voices of Poverty: Narratives of Homeless and Slum Dwelling Women of India
(State University of New York at Buffalo, 2018)This main objective of this study was intended to explore the “lived experiences” of the two sections of women who live in poverty in Patna, and in neighboring cities of Bihar in India. According to Besly et.al(2007) in ... -
3D Freeze Nano Printing for Multiscale, Multifunctional Porous Materials
(State University of New York at Buffalo, 2018)Hierarchical porous structures are ubiquitously around us (e.g., bamboo, wood, bone, bird wings). They exhibit many exceptional properties such as light weight, large surface area, and multi-functionality. It would be ... -
Fostering Students' Content Knowledge and Argumentation Skills in an Interactive Classroom Discourse with Technology-Enhanced Active Learning Instruction
(State University of New York at Buffalo, 2018)The purpose of this study was to examine how an engineering classroom community appropriates active learning discourse over a semester that promoted student content knowledge and scientific argumentation. It also assessed ... -
The Influence of Genomic Organization on the Diversity of Angiosperms
(State University of New York at Buffalo, 2018)The origin and rapid diversification of flowering plants has captured the interest of scientists across fields of study including molecular phylogenetics, evolutionary and developmental genetics, morphology, paleobotany, ... -
Development of free energy methods to study wetting behavior with molecular dynamics
(State University of New York at Buffalo, 2018)This dissertation focuses on developing molecular simulation methods to understand the wetting behavior of fluids. Within our group, we have developed an interface potential based approach for determining the interfacial ... -
Interfacial Properties of Carbon Dioxide–Water–Silica from Expanded Ensemble Monte Carlo Simulations
(State University of New York at Buffalo, 2018)This dissertation demonstrates the use of expanded ensemble Monte Carlo simulations to compute the bulk phase coexistence conditions of CO2–H2O mixtures and the interfacial properties of these mixtures over model silica ... -
Inhibitory control in adolescence: Developmental trajectories and relation to delinquent behavior
(State University of New York at Buffalo, 2018)Inhibitory control is a critical aspect of self-regulation and is hypothesized to develop throughout childhood and adolescence, reaching its peak in young adulthood. Despite its central role in several models of adolescent ... -
Holey Graphene Oxide Membranes for Water Desalination
(State University of New York at Buffalo, 2018)Holey reduced graphene oxide (r-HGO) was investigated for next-generation nanofiltration membranes for water desalination. The GO nanosheets were first etched with hydrogen peroxide to create holes to enhance the water ... -
Sanfei Clean-ups: African Traders and Guangzhou’s Urban Development from a Global Perspective
(State University of New York at Buffalo, 2018)As a beneficiary of global dispersal of manufacturing, Guangdong Province saw its light industries take off in the 1980s, which revived Guangzhou’s historical role as a trading hub. Beginning from the late 1990s, a large ... -
We'll Help Ourselves: The English Working-Class Struggle to Remake Itself, ca. 1968-1985
(State University of New York at Buffalo, 2018)“We’ll Help Ourselves: The English Working-Class Struggle to Remake Itself, 1968-1985” analyzes the changing nature of working-class activism in the United Kingdom in the second half of the twentieth century. I argue that ... -
Learner Autonomy and Vocabulary Development for Female Learners of English as a Foreign Language at a College Level in the Kingdom of Saudi Arabia
(State University of New York at Buffalo, 2018)This dissertation examines how English language learners in the Kingdom of Saudi Arabia (KSA) realize learner autonomy, especially in the context of the learner’s meaning development via purposeful vocabulary acquisition. ... -
3-Day Dietary Manipulation in Multiple Sclerosis: Impact on Exercise Performance and Fatigue
(State University of New York at Buffalo, 2018)Multiple Sclerosis (MS) is a disease characterized by inflammation of the central nervous system (CNS) leading to tissue damage. Symptoms of MS are vast and can lead to a sedentary lifestyle, fatigue, reduced exercise ... -
TEACHER AND STUDENT DISCOURSE AND VOCABULARY IN SECONDARY MATHEMATICS CLASSROOMS DURING WHOLE CLASS DISCUSSIONS
(State University of New York at Buffalo, 2018)Vocabulary and communication are essential components of mathematics that should be addressed in the classroom. Knowledge of mathematical vocabulary has been argued as a necessary building block for students to engage in ... -
Social Capital and Women Superintendents' Candidacy
(State University of New York at Buffalo, 2018)Research not only identifies a proportionately small percentage of women superintendents across the country, but also “Old Boys Networks” comprised mostly of White male superintendents and search consultants that can be ...