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Development of Photoacoustic Imaging Technologies for Biomedical Applications
(State University of New York at Buffalo, 2019)
Photoacoustic imaging (PAI) is an emerging modality based on the acoustic detection of optical absorption. Since acoustic scattering in tissue is much less than that of light, the conversion of light absorption into sound ...
Fundamentals of Nanoscale Intra-body Electromagnetic Communications at Terahertz and Optical Frequencies
(State University of New York at Buffalo, 2018)
Nanotechnology is enabling the development of biocompatible miniature implants that can detect events at the nanoscale with unprecedented accuracy. In-vivo Wireless Nanosensor Networks (iWNSNs), i.e., networks of implantable ...
Innovations in Test Phantom Metrology for Ultrasonic Imaging in relation to Medical Imaging, Biometric Characterization, and 3-Dimensional Microfluidic Applications
(State University of New York at Buffalo, 2018)
This dissertation discusses the design, fabrication, and testing of a series of test phantoms for the testing and validation of a series of applications. These test phantoms focused on the replications of key physiological ...
System Identification of Electrode-Skin Interface for Flexible PDMS Electrodes and Microelectrode Arrays
(State University of New York at Buffalo, 2019)
The objective of this research is to perform transfer function modeling of the electrode - skin interface using System Identification Toolbox (MathWorks, Inc. USA). This computational modeling is essential for developing ...
Approaches to Extract Deep Phenotypes from Clinical Data
(State University of New York at Buffalo, 2019)
Computational phenotyping is an emerging topic in health informatics. An important catalyst of this emergence is the increasing volume of clinical data available for analysis. However, clinical data typically consists of ...
CHEMICAL-FREE METAL–PDMS THERMAL BONDING IN FLEXIBLE ELECTRODE FABRICATION
(State University of New York at Buffalo, 2019)
The objective of this research is to introduce a chemical-free metal Polydimethylsiloxane (PDMS) thermal bonding (CFMPTB) in the flexible electrode fabrication by transferring metal onto a PDMS substrate. PDMS is an excellent ...
Physicomechanical Response of Ionic Polyurethanes on Endothelial Cells
(State University of New York at Buffalo, 2018)
Segmental polyurethanes (PUs) are well-characterized elastomeric biomaterials that are used in vascular graft applications. PU properties can be engineered by tuning their segmental composition and by regulating inter-segmental ...
Design of Metalloporphyrin Liposome for Biomedical Applications
(State University of New York at Buffalo, 2018)
Compared with the porphyrin, metalloporphyrin compounds are more common in nature due to the quenching phototoxicity of porphyrin by the metal chelation. Meanwhile, the metal chelation confers diverse biomedical applications ...
Microfabricated Fibrotic Microtissue Array for Screening of Potential Anti-Fibrotic Treatments
(State University of New York at Buffalo, 2018)
Fibrosis is a severe disease characterized by excessive accumulation of extracellular matrix and stiffening of the tissue during wound healing. It often leads to organ failure and has a high mortality rate. Development of ...
Development of Additive Manufactured Abdominal Aortic Aneurysm Phantoms For Minimally Invasive Endovascular Image Guided Procedures
(State University of New York at Buffalo, 2019)
With recent innovative advances in endovascular medical devices, industry attention on patient-specific healthcare solutions, and increased access to Additive Manufacturing (AM), there has been excitement to define methods ...