A Comparative Analysis of Phosphodiesterase 5 Inhibitors and Testosterone in Men with Erectile Dysfunction and Low Testosterone
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Problem under investigation: Although guidelines for the management of erectile dysfunction (ED) and testosterone deficiency exists, the treatment type in men with low testosterone is variable. Objective: To compare the effectiveness of mono and combination treatments of oral medications and testosterone therapy in men with ED and low testosterone and evaluate age, systolic blood pressure (SBP), testosterone level and body mass index (BMI) by treatment type. Theoretical framework: The life course health development model was used as the framework for this project. Method: A retrospective chart review at a urology practice in Western New York was performed to evaluate self-reported treatment effectiveness. Descriptive statistics, chi square testing, and analysis of variance were performed to analyze data. Results: The subjects were older (56%), had high SBP (64%), and obese (68%). There was no significance between treatment type and effectiveness, but combination therapy was more effective than monotherapy. There was no significant difference in mean age, SBP, testosterone level and BMI by treatment type. Conclusion: Combination therapy was clinically more effective than monotherapy for ED with low testosterone. There was no significance in mean difference in age, SBP, testosterone level or BMI for treatment type.