Quality of Life Perception Variations in Allogeneic Hematopoietic Cell Transplant Recipients with Chronic Graft Versus Host Disease and their Care Providers
MetadataShow full item record
Problem Patient reported outcome (PROs) and quality of life (QoL) perceptions vary between Hematopoietic Cell Transplant (HCT) recipients with chronic graft-versus-host disease (cGVHD), care providers, and clinicians, which may interfere with symptom management and QoL outcomes. Objectives Describe variations in perceptions of QoL between adult HCT patients with cGVHD and their care provider and clinician. Background Studies examining variations in patient-physician HCT QoL demonstrate only moderate agreement with potential underestimation of cGVHD symptom management and outcomes. Methods A descriptive, qualitative design was implemented. The FACT-BMT questionnaire was utilized in this project to create a semi-structured interview questionnaire used to explore and compare QoL perceptions among allogeneic HCT patients and their care provider and clinician. Results Results demonstrate the need to support PROs and QOL assessment in patients with cGVHD to facilitate interventions that improve overall QoL. Potential Significance This project enhances the existing evidence base of knowledge supporting the effectiveness and importance of utilizing PROs to increase QoL in HCT patients living with cGVHD. Implications Routine use of assessing PROs during outpatient HCT clinic visits can allow patients to take an active role in guiding complex treatment decisions and symptom management needs directed at improving life quality.