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MULTIPLE ACTIVITY PATTERNS OF ACETYLCHOLINE RECEPTORS
DESCRIPTION (provided by applicant): The muscle acetylcholine receptor (AChR) is an ion channel that mediates transmission at the nerve-muscle synapse. After binding two transmitter molecules, the AChR switches rapidly ...
ENGINEERING A TRANSMITTER BINDING SITE
DESCRIPTION (provided by applicant): A fundamental principle of biomedicine is that small molecules can bind to specific receptors to trigger physiological responses. We seek to understand the energetic nature of the ...