Now showing items 1-20 of 229

  • ABERRANT GABAAR TRAFFICKING AND SYNAPTIC INHIBITION IN HUNTINGTON'S DISEASE 

    YAN, ZHEN Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): Genetic studies have found that Huntington's Disease (HD) is caused by an abnormally elongated polyglutamine (polyQ) tract in the large protein huntingtin (htt). However, both the normal ...
  • ADDICTION PROPENSITY AFTER PRENATAL ETHANOL EXPOSURE 

    SHEN, ROH-YU Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): Evidence from clinical studies of fetal alcohol spectrum disorders (FASD) has shown that prenatal ethanol exposure could lead to increased propensity of addiction. Results from animal ...
  • ADOLESCENT ALCOHOL USE, SEXUAL ASSAULT AND STD/HIV RISK 

    LIVINGSTON, JENNIFER A Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): The Candidate is seeking a Mentored Research Scientist Development Award (MRSDA; K01) in order to develop an independent program of research on adolescent alcohol use, sexual risk ...
  • AFFECT AND DECISION-MAKING FOR CANCER-RELATED BEHAVIORS 

    KIVINIEMI, MARC T Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): Alleviating cancer mortality depends in part on achieving significant changes in behavior. Doing so requires a solid understanding of how and why individuals choose to engage in particular ...
  • AFFECT REGULATION TRAINING FOR ALCOHOLICS 

    STASIEWICZ, PAUL R Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): Situations involving negative affect account for nearly half of all relapses to alcohol use among men and women engaged in alcohol treatment. Despite the key role of negative affect, ...
  • AFFECT REGULATION TRAINING FOR PREGNANT SMOKERS 

    BRADIZZA, CLARA M Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): Recent data indicate that approximately one-third of women of childbearing age smoke cigarettes, and 25-50% of women smoke during pregnancy. Cigarette smoking during pregnancy is a ...
  • ALCOHOL AND VICTIMIZATION: THE ROLE OF GENDER & SEXUAL IDENTITY 

    HEQUEMBOURG, AMY L Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): A Mentored Research Scientist Development Award (MRSDA; K01) from NIAAA is sought to promote the candidate's development into a productive and independent research scientist specializing ...
  • ALCOHOL CONSEQUENCES AND PREDICTION OF SHORT-TERM CHANGES IN DRINKING BEHAVIOR 

    MERRILL, JENNIFER ELIZABETH Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): Project Summary/Abstract: Heavy alcohol use and its associated consequences are common during the college years, and are associated with deleterious short- and long-term outcomes for ...
  • ALCOHOL, RELATIONSHIP CONFLICT, AND INTIMATE PARTNER VIOLENCE 

    TESTA, MARIA L Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): Although alcohol consumption has long been recognized as a risk factor in intimate partner violence, few studies have addressed whether acute alcohol consumption is a causal factor in ...
  • ALGORITHMS FOR MOLECULAR KINETICS 

    QIN, FENG Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): QuB is a computational tool used traditionally to analyze the data from single ion channels. It is a general program capable of handling stimulus and data recording, the simulation of ...
  • ALLOSTERIC CONTROL OF NMDA RECEPTORS 

    POPESCU, GABRIELA K Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): NMDA receptors (NRs) mediate fast excitatory transmission in the brain. Their activation is critical for the normal development, maintenance and continual remodeling of excitatory ...
  • ALLOSTERIC CONTROL OF NMDA RECEPTORS 

    POPESCU, GABRIELA K Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): NMDA receptors (NRs) mediate fast excitatory transmission in the brain. Their activation is critical for the normal development, maintenance and continual remodeling of excitatory ...
  • ANIMAL MODELS OF TINNITUS, BRAIN IMAGING & THERAPY 

    SALVI, RICHARD J Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): The overall goals of this project are to (A) obtain behavioral estimates of tinnitus induced by salicylate or noise exposure, (B) identify the changes in neural activity associated with ...
  • ANTENATAL BETAMETHASONE IN LATE PRETERM GESTATION LAMBS 

    LAKSHMINRUSIMHA, SATYANARAYANA Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): The incidence of late preterm births (defined as births at 34 0/7 to 36 6/7 wk gestation) have been steadily increasing over the past decade and account for the ~ 75% of all preterm ...
  • ANTIRETROVIRAL PHARMACOLOGY TRAINING IN RESOURCE POOR COUNTRIES 

    MORSE, GENE D Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): This is a revised AITRP proposal for a postgraduate training initiative with an emphasis on HIV/AIDS clinical pharmacology between the University at Buffalo (UB) and the University of ...
  • ANTIRETROVIRAL PHARMACOLOGY TRAINING IN RESOURCE POOR COUNTRIES 

    MORSE, GENE D Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): This is a revised AITRP proposal for a postgraduate training initiative with an emphasis on HIV/AIDS clinical pharmacology between the University at Buffalo (UB) and the University of ...
  • APPLYING BEHAVIORAL ECONOMICS AND EMA TO PHYSICAL ACTIVITY AND MARIJUANA USE 

    COLLINS, R. LORRAINE Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): Marijuana is the most popular illegal substance used by emerging and young adults (age 18 to 25 years). This response to RFA-DA-09-013 uses a behavioral economics conceptual framework, ...
  • AUDITORY CORTEX PLASTICITY AND TINNITUS 

    ALLMAN, BRIAN Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): Tinnitus, a subjective perception of a phantom auditory sensation (e.g., ringing in the ears), affects approximately 10-15% of the general population. At present, there is no cure, and ...
  • BEHAVIORAL MEASURES OF TEMPORAL RESOLUTION IN MICE WITH OR WITHOUT KV1.1 SUBUNITS 

    DENT, MICHEAL L Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): The overall objective of the proposed experiments is to examine the behavioral abilities of mice to hear in several listening situations. We will test the detection of simple sounds in ...
  • BINGE DRINKING IN COUPLES AND INTIMATE PARTNER VIOLENCE 

    LEONARD, KENNETH E Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): Although frequent heavy drinking patterns are related to the occurrence of intimate partner violence (IPV) among men, the role of these women's drinking patterns in IPV is poorly ...