Now showing items 1-2 of 2

  • ENGINEERING A TRANSMITTER BINDING SITE 

    AUERBACH, ANTHONY L Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): A fundamental principle of biomedicine is that small molecules can bind to specific receptors to trigger physiological responses. We seek to understand the energetic nature of the ...
  • MULTIPLE ACTIVITY PATTERNS OF ACETYLCHOLINE RECEPTORS 

    AUERBACH, ANTHONY L Principal Investigator (2011-04-18)
    DESCRIPTION (provided by applicant): The muscle acetylcholine receptor (AChR) is an ion channel that mediates transmission at the nerve-muscle synapse. After binding two transmitter molecules, the AChR switches rapidly ...